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Sodium pyrophosphate

" in MedChemExpress (MCE) Product Catalog:

46

Inhibitors & Agonists

7

Biochemical Assay Reagents

3

Peptides

14

Natural
Products

10

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3

Isotope-Labeled Compounds

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W105970

    DiSodium pyrophosphate; Sodium acid pyrophosphate; SAPP

    Biochemical Assay Reagents Inflammation/Immunology
    Sodium pyrophosphate (Disodium pyrophosphate), a food additive, is an inorganic compound. Sodium pyrophosphate has potential hematotoxic and immunotoxic effects .
    Sodium <em>pyrophosphate</em>
  • HY-W094510

    Biochemical Assay Reagents Others
    Sodium pyrophosphate decahydrate can be as a buffering agent, a chelator and a hydrated salt nucleating agent. Sodium pyrophosphate decahydrate can also be used to a raw material for synthetic laundry scent additives .
    Sodium <em>pyrophosphate</em> decahydrate
  • HY-126370

    Endogenous Metabolite Cancer
    Geranylgeranyl pyrophosphate is a metabolite involved in protein geranylgeranylation. Geranylgeranyl pyrophosphate is the common precursor of  diterpenoids, for example, Paclitaxel. Geranylgeranyl pyrophosphate can be used for cancer research .
    Geranylgeranyl <em>pyrophosphate</em>
  • HY-113076S

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    Thiamine pyrophosphate-d3 is the deuterium labeled Thiamine pyrophosphate. Thiamine pyrophosphate is the coenzyme form of Vitamin B1 and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.
    Thiamine <em>pyrophosphate</em>-d3
  • HY-126370A

    Endogenous Metabolite Cancer
    Geranylgeranyl pyrophosphate triammonium is a metabolite involved in protein geranylgeranylation. Geranylgeranyl pyrophosphate triammonium is the common precursor of  diterpenoids, for example, Paclitaxel. Geranylgeranyl pyrophosphate triammonium can be used for cancer research .
    Geranylgeranyl <em>pyrophosphate</em> triammonium
  • HY-113037

    Farnesyl diphosphate

    TRP Channel Endogenous Metabolite Neurological Disease
    Farnesyl pyrophosphate (Farnesyl diphosphate), a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. Farnesyl pyrophosphate is a TRPM2 (TRP Channel) agonist, activates TRPM2 opening for ion influx. Farnesyl pyrophosphate is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis .
    Farnesyl <em>pyrophosphate</em>
  • HY-113076

    Endogenous Metabolite Metabolic Disease Inflammation/Immunology
    Thiamine pyrophosphate is the coenzyme form of Vitamin B1, and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex. Thiamine pyrophosphate is necessary for oxidative phosphorylation and the pentose phosphate pathway by acting as a cofactor for α-ketoacid dehydrogenases .
    Thiamine <em>pyrophosphate</em>
  • HY-113037C

    Farnesyl diphosphate ammonium

    TRP Channel Endogenous Metabolite Neurological Disease
    Farnesyl Pyrophosphate ammonium salt, a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. Farnesyl pyrophosphate ammonium salt is a TRPM2 (TRP Channel) agonist, and activates TRPM2 opening for ion influx. Farnesyl pyrophosphate ammonium salt is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis .
    Farnesyl <em>Pyrophosphate</em> ammonium
  • HY-N9474

    5-Diphosphomevalonic acid tetralithium; Mevalonic acid 5-diphosphate tetralithium

    Endogenous Metabolite Others
    Mevalonic acid 5-pyrophosphate (5-Diphosphomevalonic acid) tetralithium is an endogenous metabolite of the mevalonate pathway .
    Mevalonic acid 5-<em>pyrophosphate</em> tetralithium
  • HY-W013046

    PRPP pentaSodium

    Endogenous Metabolite Others
    Phosphoribosyl pyrophosphate (PRPP) pentasodium is an important metabolite required in the biosynthesis of purine and pyrimidine nucleotides, the amino acids histidine and tryptophan, and the cofactors NAD and NADP .
    Phosphoribosyl <em>pyrophosphate</em> pentasodium
  • HY-W127689

    Bis(tetrabutylammonium) dihydrogen diphosphate

    Biochemical Assay Reagents Others
    Bis(tetrabutylammonium) Dihydrogen Pyrophosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Bis(tetrabutylammonium) dihydrogen <em>pyrophosphate</em>
  • HY-130573

    Dimethylallyl diphosphate

    Others Metabolic Disease
    DMAPP (Dimethylallyl pyrophosphate) is an isoprenoid precursor. DMAPP, as an isomer of isopentenyl pyrophosphate (IPP), exists in virtually all life forms .
    DMAPP
  • HY-133957

    6-Fluoromevalonate; FMev

    Biochemical Assay Reagents Others
    6-Fluoromevalonate is a mevalonate-pyrophosphate decarboxylase inhibitor.
    Fluoromevalonate
  • HY-114295

    Geranyl pyrophosphate

    Endogenous Metabolite Metabolic Disease
    Geranyl diphosphate is a key intermediate in the isoprenoid biosynthesis pathway (IBP). HY-114295 plays key roles in cellular metabolism and is responsible for the production of both sterol and non-sterol isoprenoids .
    Geranyl diphosphate
  • HY-B0445
    NAD+
    Maximum Cited Publications
    21 Publications Verification

    β-DPN; β-NAD; β-Nicotinamide Adenine Dinucleotide

    Endogenous Metabolite Metabolic Disease
    NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
    NAD+
  • HY-114295A

    Geranyl pyrophosphate triammonium

    Endogenous Metabolite Metabolic Disease
    Geranyl diphosphate triammonium is a key intermediate in the isoprenoid biosynthesis pathway (IBP). Geranyl diphosphate triammonium plays key roles in cellular metabolism and is responsible for the production of both sterol and non-sterol isoprenoids .
    Geranyl diphosphate triammonium
  • HY-16011
    NE 10790
    1 Publications Verification

    3-PEHPC

    Others Others
    NE 10790, a poor farnesyl pyrophosphate synthase inhibitor, is a phosphonocarboxylate analogue of the potent bisphosphonate risedronate and is a weak antiresorptive agent.
    NE 10790
  • HY-130573A

    Dimethylallyl diphosphate triammonium

    Others Metabolic Disease
    DMAPP (Dimethylallyl diphosphate) triammonium is an isoprenoid precursor. DMAPP triammonium, as an isomer of isopentenyl pyrophosphate (IPP), exists in virtually all life forms .
    DMAPP triammonium
  • HY-P10027

    Antibiotic Bacterial Infection
    Clovibactin is an antibiotic for drug-resistant bacterial pathogens without detectable resistance. Clovibactin TFA inihibits cell wall synthesis by targeting pyrophosphate of peptidoglycan precursors .
    Clovibactin
  • HY-B0278

    Zinc bacitracin

    Bacterial Antibiotic Infection
    Bacitracin Zinc (Zinc bacitracin) is a dephosphorylation of the C55-isoprenyl pyrophosphate interference for inhibition of cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.
    Bacitracin Zinc
  • HY-161012

    Apoptosis Cancer
    RB-07-16 is a C6-PyraP-BP inhibitor of human geranylammate pyrophosphate synthase (hGGPPS). RB-07-16 has antitumor activity .
    RB-07-16
  • HY-B0445S1

    β-DPN-13C5; β-NAD-13C5; β-Nicotinamide Adenine Dinucleotide-13C5

    Endogenous Metabolite Metabolic Disease
    NAD+- 13C5-1 is the 13C labeled NAD+[1]. NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
    NAD+-13C5
  • HY-P2891

    PoxB

    Endogenous Metabolite Others
    Pyruvate Oxidase, Microorganisms (PoxB) is a thiamine pyrophosphate-dependent oxidase that catalyzes the oxidative decarboxylation of pyruvate to acetyl phosphate, carbon dioxide and water. Pyruvate oxidase is an important enzyme in bacterial metabolism and is often used in biochemical research .
    Pyruvate Oxidase, Microorganisms
  • HY-W654288

    β-DPN-d4; β-NAD-d4; β-Nicotinamide Adenine Dinucleotide-d4

    Isotope-Labeled Compounds Others
    NAD+-d4 is the deuterium-labeled NAD+ (HY-B0445). NAD+-d4 is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
    NAD+-d4
  • HY-P10027A

    Antibiotic Bacterial Infection
    Clovibactin TFA is the TFA salt form of Clovibactin (HY-P10027). Clovibactin TFA is an antibiotic for drug-resistant bacterial pathogens without detectable resistance. Clovibactin TFA inihibits cell wall synthesis by targeting pyrophosphate of peptidoglycan precursors .
    Clovibactin TFA
  • HY-N2581
    Phytic acid sodium salt
    1 Publications Verification

    myo-Inositol, hexakis(dihydrogen phosphate) Sodium salt; Inositol hexaphosphate Sodium salt

    Endogenous Metabolite Others
    Phytic acid sodium salt (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphat) is often present in legume seeds with antinutritional effects. Phytic acid sodium salt is a [PO4] 3- storage depot and precursor for other inositol phosphates and pyrophosphates. phytic acid is hydrolyzed by phytases in a stepwise manner in the plant .
    Phytic acid sodium salt
  • HY-P2992

    PPase

    Endogenous Metabolite Others
    Inorganic pyrophosphatase, Saccharomyces cerevisiae (PPase) converts pyrophosphate (PPi) to phosphate. Inorganic pyrophosphatase is an essential component of in vitro transcription reactions for RNA preparation, is often used in biochemical studies. Inorganic pyrophosphatase is critical for driving cellular processes such as nucleic acid and protein synthesis .
    Inorganic pyrophosphatase, Saccharomyces cerevisiae
  • HY-145498

    TNF Receptor Inflammation/Immunology
    HDMAPP triammonium is a potent phosphoantigen in the ammonium form and the pyrophosphate form of (E)-HDMAPP. HDMAPP is also a potent activator of γδ T cells and can induce T cell stimulation in vitro (EC50=0.39 nM, TNF-α) .
    HDMAPP triammonium
  • HY-107193

    Bacterial Antibiotic PDI Infection Cancer
    Bacitracin is a polypeptide antibiotic against staphylococcal and pathogenic protozoa infections. Bacitracin inhibits cell wall biosynthesis and permeability through binding to the undecaprenyl pyrophosphate. Bacitracin inhibits macromolecular synthesis. Bacitracin is also a protein disulfide isomerase (PDI) inhibitor .
    Bacitracin
  • HY-130837

    Bacterial Infection
    JH-LPH-28, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-28 displays outstanding antibiotic activity with a MIC value of 0.83 μg/mL .
    JH-LPH-28
  • HY-130838

    Bacterial Infection
    JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-33 displays outstanding antibiotic activity with a MIC value of 0.66 μg/mL .
    JH-LPH-33
  • HY-130836

    Bacterial Infection
    LpxH-IN-AZ1, a sulfonyl piperazine compound, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. LpxH-IN-AZ1 is a potent inhibitor of Klebsiella pneumoniae LpxH with IC50 of 0.36 μM .
    LpxH-IN-AZ1
  • HY-B0278R

    Zinc bacitracin (Standard)

    Bacterial Antibiotic Infection
    Bacitracin (Zinc) (Standard) is the analytical standard of Bacitracin (Zinc). This product is intended for research and analytical applications. Bacitracin Zinc (Zinc bacitracin) is a dephosphorylated product of C55-isoprenyl pyrophosphate and inhibits Tyr cleavage from Met-enkephalin with an IC50 of 10 μM.
    Bacitracin Zinc (Standard)
  • HY-150607

    Others Others
    UNC7467 is a potent IP6K inhibitor with values of 4.9, 8.9 and 1320 nM for IP6K2, IP6K1 and IP6K6, respectively. UNC7467 reduces levels of inositol pyrophosphates. UNC7467 can be used for obesity research .
    UNC7467
  • HY-E70028

    Endogenous Metabolite Metabolic Disease
    UDP-sugar pyrophosphorylase (BlUSP) is the enzyme capable of activating glucose-1-phosphate (Glc-1-P) to UDP-glucose (UDP-Glc). UDP-sugar pyrophosphorylase (BlUSP) catalyzes a reversible transfer of the uridyl group from UTP to sugar-1-phosphate, producing UDP-sugar and pyrophosphate (PPi) .
    UDP-sugar pyrophosphorylase (BlUSP)
  • HY-126255

    NAMPT Metabolic Disease
    SBI-797812 is an orally active nicotinamide phosphoribosyltransferase (NAMPT) activator. SBI-797812 shifts NAMPT to NMN formation, increases NAMPT affinity for ATP, stabilizes phosphorylated NAMPT, promotes consumption of the pyrophosphate by-product, and blunts feedback inhibition by NAD +. SBI-797812 increases intracellular nicotinamide mononucleotide (NMN) and elevates liver NAD + in mice .
    SBI-797812
  • HY-144129

    Apoptosis Cancer
    hGGPPS-IN-2 (Compound 16g) is a potent inhibitor of the human geranylgeranyl pyrophosphate synthase (hGGPPS). hGGPPS-IN-2 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). hGGPPS-IN-2 induces target-selective apoptosis of multiple myeloma (MM) cells and exhibits antimyeloma activity in vivo .
    hGGPPS-IN-2
  • HY-144130

    Apoptosis Cancer
    hGGPPS-IN-3 (Compound 13h) is a potent inhibitor of the human geranylgeranyl pyrophosphate synthase (hGGPPS). hGGPPS-IN-3 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). hGGPPS-IN-3 induces target-selective apoptosis of multiple myeloma (MM) cells and exhibits antimyeloma activity in vivo .
    hGGPPS-IN-3
  • HY-144128

    Apoptosis Cancer
    hGGPPS-IN-1 (Compound 18b) is a potent inhibitor of the human geranylgeranyl pyrophosphate synthase (hGGPPS). hGGPPS-IN-1 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). hGGPPS-IN-1 induces target-selective apoptosis of multiple myeloma (MM) cells and exhibits antimyeloma activity in vivo .
    hGGPPS-IN-1
  • HY-N8060A

    Orotidine monophosphate triSodium; Orotidylic acid triSodium

    Endogenous Metabolite DNA/RNA Synthesis Metabolic Disease
    Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms including M. tuberculosis, S. cerevisiae, S. typhimurium and P. falciparum to name a few. The synthesis of orotidine 5'-monophosphate trisodium uses phosphoribosyl pyrophosphate (PRPP) and orotic acid (OA) as the substrates catalyzed by orotate phosphoribosyltransferase (OPRT) .
    Orotidine 5′-monophosphate trisodium
  • HY-145064

    Phosphodiesterase (PDE) Infection Cancer
    Enpp-1-IN-6 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). The ENPP 1 has broad specificity and can cleave a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds nucleotides and nucleotide sugars. Enpp-1-IN-6 has the potential for the research of cancer and infectious diseases (extracted from patent WO2021203772A1, compound 51) .
    Enpp-1-IN-6
  • HY-145065

    Phosphodiesterase (PDE) Infection Cancer
    Enpp-1-IN-7 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). The ENPP 1 has broad specificity and can cleave a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds nucleotides and nucleotide sugars. Enpp-1-IN-7 has the potential for the research of cancer and infectious diseases (extracted from patent WO2021203772A1, compound 51) .
    Enpp-1-IN-7
  • HY-145069

    Phosphodiesterase (PDE) Cancer
    Enpp-1-IN-8 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). The ENPP 1 has broad specificity and can cleave a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds nucleotides and nucleotide sugars. Enpp-1-IN-8 has the potential for the research of cancer and infectious diseases (extracted from patent WO2021203772A1, compound 51) .
    Enpp-1-IN-8
  • HY-145070

    Phosphodiesterase (PDE) Infection Cancer
    Enpp-1-IN-9 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). The ENPP 1 has broad specificity and can cleave a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds nucleotides and nucleotide sugars. Enpp-1-IN-9 has the potential for the research of cancer and infectious diseases (extracted from patent WO2021203772A1, compound 51) .
    Enpp-1-IN-9
  • HY-145063

    Phosphodiesterase (PDE) Infection Inflammation/Immunology Cancer
    Enpp-1-IN-5 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). The ENPP 1 has broad specificity and can cleave a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds nucleotides and nucleotide sugars. Enpp-1-IN-5 has the potential for the research of cancer and infectious diseases (extracted from patent WO2019046778A1/WO2021203772A1, compound 1) .
    Enpp-1-IN-5
  • HY-153335

    Phosphodiesterase (PDE) Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Enpp-1-IN-16 (compound 54) is an ENPP1 inhibitor. Enpp-1-IN-16 has the potential to study cancer, especially in cases of high ENPP1 expression or elevated cytoplasmic DNA levels. Enpp-1-IN-16 can also be used in other diseases mediated by ENPP1, such as bacterial or viral infections, insulin resistance and type II diabetes, chondrocalcinosis and osteoarthritis, calcium pyrophosphate deposition disorder (CPPD), low Phosphatase disease and soft tissue calcification disorders .
    Enpp-1-IN-16

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